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Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence
Type three secretion systems (T3SS) are complex nano-machines that evolved to inject bacterial effector proteins directly into the cytoplasm of eukaryotic cells. Many high-priority human pathogens rely on one or more T3SSs to cause disease and evade host immune responses, underscoring the need to be...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980540/ https://www.ncbi.nlm.nih.gov/pubmed/31978132 http://dx.doi.org/10.1371/journal.pone.0228227 |