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ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain
Resistance to chronic Toxoplasma gondii infection requires ongoing recruitment of T cells to the brain. Thus, the factors that promote, sustain, and regulate the T cell response to the parasite in the brain are of great interest. The costimulatory molecule ICOS (inducible T cell costimulator) has be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980566/ https://www.ncbi.nlm.nih.gov/pubmed/31978191 http://dx.doi.org/10.1371/journal.pone.0228251 |