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ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain

Resistance to chronic Toxoplasma gondii infection requires ongoing recruitment of T cells to the brain. Thus, the factors that promote, sustain, and regulate the T cell response to the parasite in the brain are of great interest. The costimulatory molecule ICOS (inducible T cell costimulator) has be...

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Detalles Bibliográficos
Autores principales:	O’Brien, Carleigh A., Harris, Tajie H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980566/ https://www.ncbi.nlm.nih.gov/pubmed/31978191 http://dx.doi.org/10.1371/journal.pone.0228251

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