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Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10

Envelope (Env) phenotype(s) that provide transmitted founders (TF) with a selective advantage during HIV-1 transmission would be the ideal target for preventative therapy. We generated Env clones from four individuals infected with a single virus and one participant infected with multiple variants a...

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Detalles Bibliográficos
Autores principales: Lumngwena, Evelyn Ngwa, Abrahams, Bianca, Shuping, Liliwe, Cicala, Claudia, Arthos, James, Woodman, Zenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980567/
https://www.ncbi.nlm.nih.gov/pubmed/31978062
http://dx.doi.org/10.1371/journal.pone.0227533