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Are the current gRNA ranking prediction algorithms useful for genome editing in plants?

Introducing a new trait into a crop through conventional breeding commonly takes decades, but recently developed genome sequence modification technology has the potential to accelerate this process. One of these new breeding technologies relies on an RNA-directed DNA nuclease (CRISPR/Cas9) to cut th...

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Detalles Bibliográficos
Autores principales: Naim, Fatima, Shand, Kylie, Hayashi, Satomi, O’Brien, Martin, McGree, James, Johnson, Alexander A. T., Dugdale, Benjamin, Waterhouse, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980586/
https://www.ncbi.nlm.nih.gov/pubmed/31978124
http://dx.doi.org/10.1371/journal.pone.0227994