Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease

The apolipoprotein E gene (APOE) is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD), yet the expression of APOE is not clearly understood. For example, it is unclear whether AD patients have elevated or decreased APOE expression or why the correlation levels of APOE RNA and...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Gyung, Tulloch, Jessica, Chen, Sunny, Leong, Lesley, Saxton, Aleen D., Kraemer, Brian, Darvas, Martin, Keene, C. Dirk, Shutes-David, Andrew, Todd, Kaitlin, Millard, Steve, Yu, Chang-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980611/
https://www.ncbi.nlm.nih.gov/pubmed/31978088
http://dx.doi.org/10.1371/journal.pone.0227667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980611/
https://www.ncbi.nlm.nih.gov/pubmed/31978088
http://dx.doi.org/10.1371/journal.pone.0227667

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