TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC

Introduction: The impact of TP53 co-mutations in EGFR mutated patients on PFS and OS is controversial. Different classifications of TP53 mutations with respect to functional and potential clinical impact have been published. Therefore, we retrospectively analyzed the impact of TP53 co-mutations on O...

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Detalles Bibliográficos
Autores principales: Roeper, Julia, Falk, Markus, Chalaris-Rißmann, Athena, Lueers, Anne C., Ramdani, Hayat, Wedeken, Katrin, Stropiep, Ursula, Diehl, Linda, Tiemann, Markus, Heukamp, Lukas C., Otto-Sobotka, Fabian, Griesinger, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980625/
https://www.ncbi.nlm.nih.gov/pubmed/32076486
http://dx.doi.org/10.18632/oncotarget.27430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980625/
https://www.ncbi.nlm.nih.gov/pubmed/32076486
http://dx.doi.org/10.18632/oncotarget.27430

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