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TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC
Introduction: The impact of TP53 co-mutations in EGFR mutated patients on PFS and OS is controversial. Different classifications of TP53 mutations with respect to functional and potential clinical impact have been published. Therefore, we retrospectively analyzed the impact of TP53 co-mutations on O...
Autores principales: | Roeper, Julia, Falk, Markus, Chalaris-Rißmann, Athena, Lueers, Anne C., Ramdani, Hayat, Wedeken, Katrin, Stropiep, Ursula, Diehl, Linda, Tiemann, Markus, Heukamp, Lukas C., Otto-Sobotka, Fabian, Griesinger, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980625/ https://www.ncbi.nlm.nih.gov/pubmed/32076486 http://dx.doi.org/10.18632/oncotarget.27430 |
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