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Prevalence and clinical significance of VHL mutations and 3p25 deletions in renal tumor subtypes

Purpose: To evaluate prevalence and clinical impact of VHL mutations and deletions (3p), a cohort of consecutive kidney tumors was analyzed by DNA sequencing and fluorescence in-situ hybridization (FISH). Patients and Methods: The study includes 1,805 patients with renal tumors who were surgically t...

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Detalles Bibliográficos
Autores principales: Büscheck, Franziska, Fraune, Christoph, Simon, Ronald, Kluth, Martina, Hube-Magg, Claudia, Möller-Koop, Christina, Sarper, Imren, Ketterer, Kathrin, Henke, Tjark, Eichelberg, Christian, Dahlem, Roland, Wilczak, Waldemar, Sauter, Guido, Fisch, Margit, Eichenauer, Till, Rink, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980626/
https://www.ncbi.nlm.nih.gov/pubmed/32076485
http://dx.doi.org/10.18632/oncotarget.27428