PDGFRA defines the mesenchymal stem cell Kaposi’s sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment

Kaposi’s sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). Unanswered questions regarding KS are its cellular ontology and the conditions conducive to viral oncogenesis. We identify PDGFRA(+)/SCA-1(+) bone marrow-derived mesenchymal stem cells (Pα(+)S MSCs) as K...

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Detalles Bibliográficos
Autores principales: Naipauer, Julian, Rosario, Santas, Gupta, Sachin, Premer, Courtney, Méndez-Solís, Omayra, Schlesinger, Mariana, Ponzinibbio, Virginia, Jain, Vaibhav, Gay, Lauren, Renne, Rolf, Chan, Ho Lam, Morey, Lluis, Salyakina, Daria, Abba, Martin, Williams, Sion, Hare, Joshua M., Goldschmidt-Clermont, Pascal J., Mesri, Enrique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980685/
https://www.ncbi.nlm.nih.gov/pubmed/31881074
http://dx.doi.org/10.1371/journal.ppat.1008221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980685/
https://www.ncbi.nlm.nih.gov/pubmed/31881074
http://dx.doi.org/10.1371/journal.ppat.1008221

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