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The role of actin protrusion dynamics in cell migration through a degradable viscoelastic extracellular matrix: Insights from a computational model

Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D) cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (ECM), mechanically probe the ECM and contract in order to displace the cell body. This results in cell migration t...

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Detalles Bibliográficos
Autores principales: Heck, Tommy, Vargas, Diego A., Smeets, Bart, Ramon, Herman, Van Liedekerke, Paul, Van Oosterwyck, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980736/
https://www.ncbi.nlm.nih.gov/pubmed/31929522
http://dx.doi.org/10.1371/journal.pcbi.1007250