Cargando…
The role of actin protrusion dynamics in cell migration through a degradable viscoelastic extracellular matrix: Insights from a computational model
Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D) cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (ECM), mechanically probe the ECM and contract in order to displace the cell body. This results in cell migration t...
Autores principales: | Heck, Tommy, Vargas, Diego A., Smeets, Bart, Ramon, Herman, Van Liedekerke, Paul, Van Oosterwyck, Hans |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980736/ https://www.ncbi.nlm.nih.gov/pubmed/31929522 http://dx.doi.org/10.1371/journal.pcbi.1007250 |
Ejemplares similares
-
Modeling of Mechanosensing Mechanisms Reveals Distinct Cell Migration Modes to Emerge From Combinations of Substrate Stiffness and Adhesion Receptor–Ligand Affinity
por: Vargas, Diego A., et al.
Publicado: (2020) -
Analysis of Initial Cell Spreading Using Mechanistic Contact Formulations for a Deformable Cell Model
por: Odenthal, Tim, et al.
Publicado: (2013) -
Actin-Based Cell Protrusion in a 3D Matrix
por: Caswell, Patrick T., et al.
Publicado: (2018) -
Steering cell migration by alternating blebs and actin-rich protrusions
por: Diz-Muñoz, Alba, et al.
Publicado: (2016) -
E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow
por: Grimaldi, Cecilia, et al.
Publicado: (2020)