The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing

Alternative splicing has been shown to causally contribute to the epithelial–mesenchymal transition (EMT) and tumor metastasis. However, the scope of splicing factors that govern alternative splicing in these processes remains largely unexplored. Here we report the identification of A-Kinase Anchor...

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Detalles Bibliográficos
Autores principales: Hu, Xiaohui, Harvey, Samuel E., Zheng, Rong, Lyu, Jingyi, Grzeskowiak, Caitlin L., Powell, Emily, Piwnica-Worms, Helen, Scott, Kenneth L., Cheng, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981122/
https://www.ncbi.nlm.nih.gov/pubmed/31980632
http://dx.doi.org/10.1038/s41467-020-14304-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981122/
https://www.ncbi.nlm.nih.gov/pubmed/31980632
http://dx.doi.org/10.1038/s41467-020-14304-1

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