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Hypoxic environment may enhance migration/penetration of endocrine resistant MCF7- derived breast cancer cells through monolayers of other non-invasive cancer cells in vitro

The response of cancer cells to hypoxic conditions found within the interior of a tumor mass is mediated through the hypoxia inducible factor (HIF) cascade and is thought to promote metastasis. However, given their distant proximity from blood vessels as compared to normoxic cells at the vascularise...

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Detalles Bibliográficos
Autores principales: Barrak, Nora H., Khajah, Maitham A., Luqmani, Yunus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981140/
https://www.ncbi.nlm.nih.gov/pubmed/31980706
http://dx.doi.org/10.1038/s41598-020-58055-x