pVHL-mediated regulation of the anti-angiogenic protein thrombospondin-1 decreases migration of Clear Cell Renal Carcinoma Cell Lines

Thrombospondin-1 (TSP-1) is a multifunctional matrix protein with antitumor activities due in part to its ability to inhibit angiogenesis, which in turn contributes to determine the fate of many tumours. Previous studies have shown that TSP-1 expression supports normal kidney angiostasis, and decrea...

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Detalles Bibliográficos
Autores principales: Sevilla-Montero, Javier, Bienes-Martínez, Raquel, Labrousse-Arias, David, Fuertes-Yebra, Esther, Ordóñez, Ángel, Calzada, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981148/
https://www.ncbi.nlm.nih.gov/pubmed/31980715
http://dx.doi.org/10.1038/s41598-020-58137-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981148/
https://www.ncbi.nlm.nih.gov/pubmed/31980715
http://dx.doi.org/10.1038/s41598-020-58137-w

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