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An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells

The cadherin-catenin complex at adherens junctions (AJs) is essential for the formation of cell-cell adhesion and epithelium integrity; however, studying the dynamic regulation of AJs at high spatio-temporal resolution remains challenging. Here we present an optochemical tool which allows reconstitu...

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Detalles Bibliográficos
Autores principales: Ollech, Dirk, Pflästerer, Tim, Shellard, Adam, Zambarda, Chiara, Spatz, Joachim Pius, Marcq, Philippe, Mayor, Roberto, Wombacher, Richard, Cavalcanti-Adam, Elisabetta Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981158/
https://www.ncbi.nlm.nih.gov/pubmed/31980653
http://dx.doi.org/10.1038/s41467-020-14390-1