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An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells
The cadherin-catenin complex at adherens junctions (AJs) is essential for the formation of cell-cell adhesion and epithelium integrity; however, studying the dynamic regulation of AJs at high spatio-temporal resolution remains challenging. Here we present an optochemical tool which allows reconstitu...
Autores principales: | Ollech, Dirk, Pflästerer, Tim, Shellard, Adam, Zambarda, Chiara, Spatz, Joachim Pius, Marcq, Philippe, Mayor, Roberto, Wombacher, Richard, Cavalcanti-Adam, Elisabetta Ada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981158/ https://www.ncbi.nlm.nih.gov/pubmed/31980653 http://dx.doi.org/10.1038/s41467-020-14390-1 |
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