Adenylosuccinic acid therapy ameliorates murine Duchenne Muscular Dystrophy

Arising from the ablation of the cytoskeletal protein dystrophin, Duchenne Muscular Dystrophy (DMD) is a debilitating and fatal skeletal muscle wasting disease underpinned by metabolic insufficiency. The inability to facilitate adequate energy production may impede calcium (Ca(2+)) buffering within,...

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Detalles Bibliográficos
Autores principales: Timpani, Cara A., Goodman, Craig A., Stathis, Christos G., White, Jason D., Mamchaoui, Kamel, Butler-Browne, Gillian, Gueven, Nuri, Hayes, Alan, Rybalka, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981178/
https://www.ncbi.nlm.nih.gov/pubmed/31980663
http://dx.doi.org/10.1038/s41598-020-57610-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981178/
https://www.ncbi.nlm.nih.gov/pubmed/31980663
http://dx.doi.org/10.1038/s41598-020-57610-w

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