Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome

Cockayne syndrome (CS) is a rare genetic disorder caused by mutations (dysfunction) in CSA and CSB. CS patients exhibit mild photosensitivity and severe neurological problems. Currently, CS diagnosis is based on the inefficiency of CS cells to recover RNA synthesis upon genotoxic (UV) stress. Indeed...

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Detalles Bibliográficos
Autores principales: Epanchintsev, Alexey, Rauschendorf, Marc-Alexander, Costanzo, Federico, Calmels, Nadege, Obringer, Cathy, Sarasin, Alain, Coin, Frederic, Laugel, Vincent, Egly, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981198/
https://www.ncbi.nlm.nih.gov/pubmed/31980658
http://dx.doi.org/10.1038/s41598-020-57999-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981198/
https://www.ncbi.nlm.nih.gov/pubmed/31980658
http://dx.doi.org/10.1038/s41598-020-57999-4

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