Cargando…

DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regions

Regulation of transcription occurs in a cell type specific manner orchestrated by epigenetic mechanisms including DNA methylation. Methylation changes may also play a key role in lineage specification during stem cell differentiation. To further our understanding of epigenetic regulation in chondroc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barter, Matt J., Bui, Catherine, Cheung, Kathleen, Falk, Julia, Gómez, Rodolfo, Skelton, Andrew J., Elliott, Hannah R., Reynard, Louise N., Young, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981252/ https://www.ncbi.nlm.nih.gov/pubmed/31980739 http://dx.doi.org/10.1038/s41598-020-58093-5

Ejemplares similares

Histone ChIP‐Seq identifies differential enhancer usage during chondrogenesis as critical for defining cell‐type specificity
por: Cheung, Kathleen, et al.
Publicado: (2020)

Collagen hydrogel viscoelasticity regulates MSC chondrogenesis in a ROCK-dependent manner
por: Huang, Danyang, et al.
Publicado: (2023)

Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-β
por: Hsieh, Chen-Chan, et al.
Publicado: (2023)

NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man
por: Pountos, Ippokratis, et al.
Publicado: (2011)

Effects of platelet rich plasma and chondrocyte co-culture on MSC chondrogenesis, hypertrophy and pathological responses
por: Ramezanifard, Rouhallah, et al.
Publicado: (2017)

Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p
por: Barter, Matt J., et al.
Publicado: (2015)

TGF-β Signalling is Suppressed under Pro-Hypertrophic Conditions in MSC Chondrogenesis Due to TGF-β Receptor Downregulation
por: Pfeifer, Christian G., et al.
Publicado: (2019)

Predicting and Promoting Human Bone Marrow MSC Chondrogenesis by Way of TGFβ Receptor Profiles: Toward Personalized Medicine
por: Rothweiler, René, et al.
Publicado: (2020)

Wnt antagonism without TGFβ induces rapid MSC chondrogenesis via increasing AJ interactions and restricting lineage commitment
por: Hsieh, Chen-Chan, et al.
Publicado: (2022)

Venetoclax and Hypomethylating Agents as First-line Treatment in Newly Diagnosed Patients with AML in a Predominately Community Setting in the US
por: Vachhani, Pankit, et al.
Publicado: (2022)

Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis
por: Alvarez, Hector, et al.
Publicado: (2011)

The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells
por: Barter, Matt J., et al.
Publicado: (2017)

A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5
por: Ratnayake, Madhushika, et al.
Publicado: (2017)

Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration
por: Bello, Alvin Bacero, et al.
Publicado: (2021)

Mechanical regulation of chondrogenesis
por: O’Conor, Christopher J, et al.
Publicado: (2013)

Correction: Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis
por: Alvarez, Hector, et al.
Publicado: (2011)

Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding
por: Mirvis, Mary, et al.
Publicado: (2019)

Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain
por: Nomura, Takeshi, et al.
Publicado: (2016)

Transcription mechanism of chondrogenesis
por: Asahara, H
Publicado: (2003)

Roles of microRNAs in prenatal chondrogenesis, postnatal chondrogenesis and cartilage-related diseases
por: Shang, Jin, et al.
Publicado: (2013)

DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation
por: Gómez, Rodolfo, et al.
Publicado: (2023)

CHONDROGENESIS, STUDIED WITH THE ELECTRON MICROSCOPE
por: Godman, Gabriel C., et al.
Publicado: (1960)

The Janus Role of Adhesion in Chondrogenesis
por: Casanellas, Ignasi, et al.
Publicado: (2020)

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
por: Reynard, Louise N., et al.
Publicado: (2014)

Device-Based Enrichment of Knee Joint Synovial Cells to Drive MSC Chondrogenesis Without Prior Culture Expansion In Vitro: A Step Closer to 1-Stage Orthopaedic Procedures
por: Altaie, Ala, et al.
Publicado: (2021)

Cytokine Selection of MSC Clones with Different Functionality
por: Selich, Anton, et al.
Publicado: (2019)

Cardiomyopathic troponin mutations predominantly occur at its interface with actin and tropomyosin
por: Tobacman, Larry S., et al.
Publicado: (2021)

Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis
por: Rushton, Michael D, et al.
Publicado: (2014)

SOMITE CHONDROGENESIS : A Structural Analysis
por: Minor, Ronald R.
Publicado: (1973)

Chondrogenesis, joint formation, and cartilage metabolism
por: Goldring, Mary B
Publicado: (2012)

Platelet-rich plasma application in chondrogenesis
por: Kabiri, Azadeh, et al.
Publicado: (2014)

Current Understanding on the Molecular Basis of Chondrogenesis
por: Michigami, Toshimi
Publicado: (2014)

Oxytocin Controls Chondrogenesis and Correlates with Osteoarthritis
por: Roux, Christian H., et al.
Publicado: (2020)

TAZ is required for chondrogenesis and skeletal development
por: Li, Yang, et al.
Publicado: (2021)

Extracellular Vesicles in chondrogenesis and Cartilage regeneration
por: Song, Hong, et al.
Publicado: (2021)

How and When Does Outcrossing Occur in the Predominantly Selfing Species Medicago truncatula?
por: Jullien, Margaux, et al.
Publicado: (2021)

Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874
por: Shepherd, Colin, et al.
Publicado: (2015)

Jessie Dobson, MSc.
por: LeFanu, W
Publicado: (1985)

Synchro-Cyclotron (MSC)
Publicado: (1964)

Synchro-Cyclotron (MSC)
Publicado: (1965)

Cannot write session to /tmp/vufind_sessions/sess_2ju3pndq2mc3rr24hk24pfikvl