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The Splicing Factor hnRNP M Is a Critical Regulator of Innate Immune Gene Expression in Macrophages

While transcriptional control of innate immune gene expression is well characterized, almost nothing is known about how pre-mRNA splicing decisions influence, or are influenced by, macrophage activation. Here, we demonstrate that the splicing factor hnRNP M is a critical repressor of innate immune g...

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Detalles Bibliográficos
Autores principales: West, Kelsi O., Scott, Haley M., Torres-Odio, Sylvia, West, A. Phillip, Patrick, Kristin L., Watson, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981299/
https://www.ncbi.nlm.nih.gov/pubmed/31693898
http://dx.doi.org/10.1016/j.celrep.2019.09.078