Binding of HasA by its transmembrane receptor HasR follows a conformational funnel mechanism

HasR in the outer membrane of Serratia marcescens binds secreted, heme-loaded HasA and translocates the heme to the periplasm to satisfy the cell’s demand for iron. The previously published crystal structure of the wild-type complex showed HasA in a very specific binding arrangement with HasR, apt t...

Descripción completa

Detalles Bibliográficos
Autores principales: Exner, Thomas E., Becker, Stefanie, Becker, Simon, Boniface-Guiraud, Audrey, Delepelaire, Philippe, Diederichs, Kay, Welte, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981324/
https://www.ncbi.nlm.nih.gov/pubmed/31802151
http://dx.doi.org/10.1007/s00249-019-01411-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981324/
https://www.ncbi.nlm.nih.gov/pubmed/31802151
http://dx.doi.org/10.1007/s00249-019-01411-1

Ejemplares similares