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MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity
Aortic valve interstitial cells (AVICs) play a major role in valvular calcification associated with calcific aortic valve disease (CAVD). Although AVICs from diseased valves display a pro-osteogenic phenotype, the underlying mechanism causing this remains unclear. MicroRNA-204 (miR-204) is a negativ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981435/ https://www.ncbi.nlm.nih.gov/pubmed/31861929 http://dx.doi.org/10.3390/ijms21010076 |