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MicroRNA-204 Deficiency in Human Aortic Valves Elevates Valvular Osteogenic Activity

Aortic valve interstitial cells (AVICs) play a major role in valvular calcification associated with calcific aortic valve disease (CAVD). Although AVICs from diseased valves display a pro-osteogenic phenotype, the underlying mechanism causing this remains unclear. MicroRNA-204 (miR-204) is a negativ...

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Detalles Bibliográficos
Autores principales: Song, Rui, Zhai, Yufeng, Ao, Lihua, Fullerton, David A., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981435/
https://www.ncbi.nlm.nih.gov/pubmed/31861929
http://dx.doi.org/10.3390/ijms21010076