Harnessing the Effects of BTKi on T Cells for Effective Immunotherapy against CLL

B-cell receptor (BCR) signaling and tumor–microenvironment crosstalk both drive chronic lymphocytic leukemia (CLL) pathogenesis. Within the microenvironment, tumor cells shape the T-cell compartment, which in turn supports tumor growth and survival. Targeting BCR signaling using Bruton tyrosine kina...

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Detalles Bibliográficos
Autores principales: Mhibik, Maissa, Wiestner, Adrian, Sun, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981459/
https://www.ncbi.nlm.nih.gov/pubmed/31861854
http://dx.doi.org/10.3390/ijms21010068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981459/
https://www.ncbi.nlm.nih.gov/pubmed/31861854
http://dx.doi.org/10.3390/ijms21010068

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