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Defects in G-Actin Incorporation into Filaments in Myoblasts Derived from Dysferlinopathy Patients Are Restored by Dysferlin C2 Domains

Dysferlin is a transmembrane C-2 domain-containing protein involved in vesicle trafficking and membrane remodeling in skeletal muscle cells. However, the mechanism by which dysferlin regulates these cellular processes remains unclear. Since actin dynamics is critical for vesicle trafficking and memb...

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Detalles Bibliográficos
Autores principales: Báez-Matus, Ximena, Figueroa-Cares, Cindel, Gónzalez-Jamett, Arlek M., Almarza-Salazar, Hugo, Arriagada, Christian, Maldifassi, María Constanza, Guerra, María José, Mouly, Vincent, Bigot, Anne, Caviedes, Pablo, Cárdenas, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981584/
https://www.ncbi.nlm.nih.gov/pubmed/31861684
http://dx.doi.org/10.3390/ijms21010037