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The Evolving Protein Engineering in the Design of Chimeric Antigen Receptor T Cells
The clinical success of chimeric antigen receptor (CAR) T cell immunotherapy in the treatment of haematological cancers has encouraged the extensive development of CAR design to improve their function and increase their applicability. Advancements in protein engineering have seen modifications to bo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981602/ https://www.ncbi.nlm.nih.gov/pubmed/31892219 http://dx.doi.org/10.3390/ijms21010204 |