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Identification of Nanobodies against the Acute Myeloid Leukemia Marker CD33

Nanobodies (Nbs) are the smallest antigen-binding, single domain fragments derived from heavy-chain-only antibodies from Camelidae. Among the several advantages over conventional monoclonal antibodies, their small size (12–15 kDa) allows them to extravasate rapidly, to show improved tissue penetrati...

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Detalles Bibliográficos
Autores principales: Romão, Ema, Krasniqi, Ahmet, Maes, Laila, Vandenbrande, Camille, Sterckx, Yann G.-J., Stijlemans, Benoit, Vincke, Cécile, Devoogdt, Nick, Muyldermans, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981622/
https://www.ncbi.nlm.nih.gov/pubmed/31906437
http://dx.doi.org/10.3390/ijms21010310