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In Silico and In Cell Analysis of Openable DNA Nanocages for miRNA Silencing

A computational and experimental integrated approach was applied in order to study the effect of engineering four DNA hairpins into an octahedral truncated DNA nanocage, to obtain a nanostructure able to recognize and bind specific oligonucleotide sequences. Modeling and classical molecular dynamics...

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Detalles Bibliográficos
Autores principales: Raniolo, Sofia, Iacovelli, Federico, Unida, Valeria, Desideri, Alessandro, Biocca, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981788/
https://www.ncbi.nlm.nih.gov/pubmed/31861821
http://dx.doi.org/10.3390/ijms21010061