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In Silico and In Cell Analysis of Openable DNA Nanocages for miRNA Silencing
A computational and experimental integrated approach was applied in order to study the effect of engineering four DNA hairpins into an octahedral truncated DNA nanocage, to obtain a nanostructure able to recognize and bind specific oligonucleotide sequences. Modeling and classical molecular dynamics...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981788/ https://www.ncbi.nlm.nih.gov/pubmed/31861821 http://dx.doi.org/10.3390/ijms21010061 |