Conformational Plasticity of the Active Site Entrance in E. coli Aspartate Transcarbamoylase and Its Implication in Feedback Regulation

Aspartate transcarbamoylase (ATCase) has been studied for decades and Escherichia coli ATCase is referred as a “textbook example” for both feedback regulation and cooperativity. However, several critical questions about the catalytic and regulatory mechanisms of E. coli ATCase remain unanswered, esp...

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Detalles Bibliográficos
Autores principales: Lei, Zhen, Wang, Nan, Tan, Hongwei, Zheng, Jimin, Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981877/
https://www.ncbi.nlm.nih.gov/pubmed/31947715
http://dx.doi.org/10.3390/ijms21010320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981877/
https://www.ncbi.nlm.nih.gov/pubmed/31947715
http://dx.doi.org/10.3390/ijms21010320

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