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Association of Drug Metabolic Enzyme Genetic Polymorphisms and Adverse Drug Reactions in Patients Receiving Rifapentine and Isoniazid Therapy for Latent Tuberculosis

Weekly rifapentine and isoniazid therapy (3HP) is the most frequent treatment for latent tuberculosis infection (LTBI). However, the association between major adverse drug reactions (ADRs) and drug metabolic enzyme single-nucleotide polymorphisms (SNPs) remains unclear. In this study, 377 participan...

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Detalles Bibliográficos
Autores principales: Yu, Ya-Yen, Tsao, Shih-Ming, Yang, Wen-Ta, Huang, Wei-Chang, Lin, Ching-Hsiung, Chen, Wei-Wen, Yang, Shun-Fa, Chiou, Hui-Ling, Huang, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981901/
https://www.ncbi.nlm.nih.gov/pubmed/31892222
http://dx.doi.org/10.3390/ijerph17010210