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N-Butyldeoxygalactonojirimycin Induces Reversible Infertility in Male CD Rats

This study shows for the first time that an iminosugar exerts anti-spermiogenic effect, inducing reversible infertility in a species that is not related to C57BL/6 male mice. In CD rats, N-butyldeoxygalactonojirimycin (NB-DGJ) caused reversible infertility at 150 mg/kg/day when administered daily as...

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Detalles Bibliográficos
Autores principales: Gupta, Vijayalaxmi, Hild, Sheri A., Jakkaraj, Sudhakar R., Carlson, Erick J., Wong, Henry L., Allen, C. Leigh, Georg, Gunda I., Tash, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982022/
https://www.ncbi.nlm.nih.gov/pubmed/31906257
http://dx.doi.org/10.3390/ijms21010301