Alpha-Tocotrienol Prevents Oxidative Stress-Mediated Post-Translational Cleavage of Bcl-xL in Primary Hippocampal Neurons

B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic member of the Bcl2 family of proteins, which supports neurite outgrowth and neurotransmission by improving mitochondrial function. During excitotoxic stimulation, however, Bcl-xL undergoes post-translational cleavage to ∆N-Bcl-xL, and accumul...

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Detalles Bibliográficos
Autores principales: Park, Han-A, Mnatsakanyan, Nelli, Broman, Katheryn, Davis, Abigail U., May, Jordan, Licznerski, Pawel, Crowe-White, Kristi M., Lackey, Kimberly H., Jonas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982044/
https://www.ncbi.nlm.nih.gov/pubmed/31905614
http://dx.doi.org/10.3390/ijms21010220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982044/
https://www.ncbi.nlm.nih.gov/pubmed/31905614
http://dx.doi.org/10.3390/ijms21010220

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