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Alpha-Tocotrienol Prevents Oxidative Stress-Mediated Post-Translational Cleavage of Bcl-xL in Primary Hippocampal Neurons

B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic member of the Bcl2 family of proteins, which supports neurite outgrowth and neurotransmission by improving mitochondrial function. During excitotoxic stimulation, however, Bcl-xL undergoes post-translational cleavage to ∆N-Bcl-xL, and accumul...

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Detalles Bibliográficos
Autores principales:	Park, Han-A, Mnatsakanyan, Nelli, Broman, Katheryn, Davis, Abigail U., May, Jordan, Licznerski, Pawel, Crowe-White, Kristi M., Lackey, Kimberly H., Jonas, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982044/ https://www.ncbi.nlm.nih.gov/pubmed/31905614 http://dx.doi.org/10.3390/ijms21010220

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