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Autophagy is Activated In Vivo during Trimethyltin-Induced Apoptotic Neurodegeneration: A Study in the Rat Hippocampus

Trimethyltin (TMT) is an organotin compound known to produce significant and selective neuronal degeneration and reactive astrogliosis in the rodent central nervous system. Autophagy is the main cellular mechanism for degrading and recycling protein aggregates and damaged organelles, which in differ...

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Detalles Bibliográficos
Autores principales: Ceccariglia, Sabrina, Alvino, Alessandra, Del Fà, Aurora, Parolini, Ornella, Michetti, Fabrizio, Gangitano, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982133/
https://www.ncbi.nlm.nih.gov/pubmed/31881802
http://dx.doi.org/10.3390/ijms21010175