The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms

p53 is one of the most studied tumor suppressor proteins that plays an important role in basic biological processes including cell cycle, DNA damage response, apoptosis, and senescence. The human TP53 gene contains alternative promoters that produce N-terminally truncated proteins and can produce se...

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Detalles Bibliográficos
Autores principales: Porubiaková, Otília, Bohálová, Natália, Inga, Alberto, Vadovičová, Natália, Coufal, Jan, Fojta, Miroslav, Brázda, Václav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982142/
https://www.ncbi.nlm.nih.gov/pubmed/31878115
http://dx.doi.org/10.3390/ijms21010127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982142/
https://www.ncbi.nlm.nih.gov/pubmed/31878115
http://dx.doi.org/10.3390/ijms21010127

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