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How the Other Half Lives: What p53 Does When It Is Not Being a Transcription Factor

It has been four decades since the discovery of p53, the designated ‘Guardian of the Genome’. P53 is primarily known as a master transcription factor and critical tumor suppressor, with countless studies detailing the mechanisms by which it regulates a host of gene targets and their consequent signa...

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Detalles Bibliográficos
Autores principales: Ho, Teresa, Tan, Ban Xiong, Lane, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982169/
https://www.ncbi.nlm.nih.gov/pubmed/31861395
http://dx.doi.org/10.3390/ijms21010013