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Human Molecular Chaperone Hsp60 and Its Apical Domain Suppress Amyloid Fibril Formation of α-Synuclein

Heat shock proteins play roles in assisting other proteins to fold correctly and in preventing the aggregation and accumulation of proteins in misfolded conformations. However, the process of aging significantly degrades this ability to maintain protein homeostasis. Consequently, proteins with incor...

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Detalles Bibliográficos
Autores principales: Yamamoto, Hanae, Fukui, Naoya, Adachi, Mayuka, Saiki, Eiichi, Yamasaki, Anna, Matsumura, Rio, Kuroyanagi, Daichi, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982183/
https://www.ncbi.nlm.nih.gov/pubmed/31861692
http://dx.doi.org/10.3390/ijms21010047