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Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos

The G protein-coupled cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), and their endocannabinoid (eCBs) ligands, have been implicated in several aspects of brain wiring during development. Here we aim to assess whether interfering with CB1R affects development, neuritogenesis and pathfinding o...

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Detalles Bibliográficos
Autores principales: Zuccarini, Giulia, D’Atri, Ilaria, Cottone, Erika, Mackie, Ken, Shainer, Inbal, Gothilf, Yoav, Provero, Paolo, Bovolin, Patrizia, Merlo, Giorgio Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982252/
https://www.ncbi.nlm.nih.gov/pubmed/31881740
http://dx.doi.org/10.3390/ijms21010168