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Proteomic analysis of degradation ubiquitin signaling by ubiquitin occupancy changes responding to 26S proteasome inhibition

BACKGROUND: Ubiquitination is a post-translational modification where ubiquitin is covalently attached to lysine residues on substrate proteins to signal their degradation by the 26S proteasome or initiate other non-degradation functions such as cellular trafficking. The diversity of ubiquitin modif...

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Detalles Bibliográficos
Autores principales: Hristova, Ventzislava, Sun, Shisheng, Zhang, Hui, Chan, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982382/
https://www.ncbi.nlm.nih.gov/pubmed/31997977
http://dx.doi.org/10.1186/s12014-020-9265-x