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The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells

BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical, adversely affecting reproductive processes. The well-characterized canonical mechanism of TCDD action involves the activation of aryl hydrocarbon receptor (AhR) pathway, but AhR-independent mechanisms were also sugg...

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Detalles Bibliográficos
Autores principales: Ruszkowska, Monika, Sadowska, Agnieszka, Nynca, Anna, Orlowska, Karina, Swigonska, Sylwia, Molcan, Tomasz, Paukszto, Lukasz, Jastrzebski, Jan P., Ciereszko, Renata E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982409/
https://www.ncbi.nlm.nih.gov/pubmed/32002328
http://dx.doi.org/10.7717/peerj.8371