An Imatinib–non‐responsive patient with an ABL Leu387Trp mutation achieves cytogenetic and molecular response under bosutinib: Case report and biological characterization

Leu387Trp mutation, aroused in an imatinib‐non‐responsive CML patient, was selected by imatinib treatment along with other unknown factors responsible for resistance, and then it was overcome by bosutinib. These results will be useful for treating patients with this rare mutation and will advise aga...

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Detalles Bibliográficos
Autores principales: Crespiatico, Ilaria, Bossi, Elisa, Brioschi, Filippo, Piazza, Rocco, Mologni, Luca, Gambacorti‐Passerini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982521/
https://www.ncbi.nlm.nih.gov/pubmed/31998490
http://dx.doi.org/10.1002/ccr3.2531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982521/
https://www.ncbi.nlm.nih.gov/pubmed/31998490
http://dx.doi.org/10.1002/ccr3.2531

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