Quantitative evidence for early metastatic seeding in colorectal cancer

Both the timing and molecular determinants of metastasis are unknown, hindering treatment and prevention efforts. Here we characterize the evolutionary dynamics of this lethal process by analyzing exome sequencing data from 118 biopsies from 23 colorectal cancer (CRC) patients with metastases to the...

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Detalles Bibliográficos
Autores principales: Hu, Zheng, Ding, Jie, Ma, Zhicheng, Sun, Ruping, Seoane, Jose A., Shaffer, J. Scott, Suarez, Carlos J, Berghoff, Anna S, Cremolini, Chiara, Falcone, Alfredo, Loupakis, Fotios, Birner, Peter, Preusser, Matthias, Lenz, Heinz-Josef, Curtis, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982526/
https://www.ncbi.nlm.nih.gov/pubmed/31209394
http://dx.doi.org/10.1038/s41588-019-0423-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982526/
https://www.ncbi.nlm.nih.gov/pubmed/31209394
http://dx.doi.org/10.1038/s41588-019-0423-x

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