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Aberrant Promoter Hypermethylation of RASSF1a and BRCA1 in Circulating Cell-Free Tumor DNA Serves as a Biomarker of Ovarian Carcinoma

OBJECTIVE: Ovarian cancer is one of the leading causes of cancer deaths in women. Ovarian cancer is diagnosed at the late stages and generally relapses within 12-14 months of cytoreductive surgery. This is attributed to lack of precise molecular detection methodologies to detect and track the diseas...

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Detalles Bibliográficos
Autores principales: S, Sandeep Kumar, Swamy, Shalini N, Premalatha, C S, Pallavi, V R, Gawari, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982682/
https://www.ncbi.nlm.nih.gov/pubmed/31653147
http://dx.doi.org/10.31557/APJCP.2019.20.10.3001