Cancer-Specific hNQO1-Responsive Biocompatible Naphthalimides Providing a Rapid Fluorescent Turn-On with an Enhanced Enzyme Affinity

Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is overexpressed in cancer cells and associated with the drug resistance factor of cancer. The objective of this work is the development of fluorescent probes for the efficient detection of hNQO1 activity in cancer cells, which can be employed for the c...

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Detalles Bibliográficos
Autores principales: Park, Sun Young, Jung, Eugeine, Kim, Jong Seung, Chi, Sung-Gil, Lee, Min Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982707/
https://www.ncbi.nlm.nih.gov/pubmed/31861836
http://dx.doi.org/10.3390/s20010053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982707/
https://www.ncbi.nlm.nih.gov/pubmed/31861836
http://dx.doi.org/10.3390/s20010053

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