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Cancer-Specific hNQO1-Responsive Biocompatible Naphthalimides Providing a Rapid Fluorescent Turn-On with an Enhanced Enzyme Affinity
Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is overexpressed in cancer cells and associated with the drug resistance factor of cancer. The objective of this work is the development of fluorescent probes for the efficient detection of hNQO1 activity in cancer cells, which can be employed for the c...
Autores principales: | Park, Sun Young, Jung, Eugeine, Kim, Jong Seung, Chi, Sung-Gil, Lee, Min Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982707/ https://www.ncbi.nlm.nih.gov/pubmed/31861836 http://dx.doi.org/10.3390/s20010053 |
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