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Astaxanthin Protects PC12 Cells against Homocysteine- and Glutamate-Induced Neurotoxicity

Memory impairment has been shown to be associated with glutamate (Glu) excitotoxicity, homocysteine (Hcy) accumulation, and oxidative stress. We hypothesize that Glu and Hcy could damage neuronal cells, while astaxanthin (ATX) could be beneficial to alleviate the adverse effects. Using PC12 cell mod...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Huang, Chen, Kuan-Chou, Liaw, Kuo-Chun, Peng, Chiung-Chi, Peng, Robert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982875/
https://www.ncbi.nlm.nih.gov/pubmed/31948056
http://dx.doi.org/10.3390/molecules25010214