Antitumor Effect of a Novel Spiro-Acridine Compound is Associated with Up-Regulation of Th1-Type Responses and Antiangiogenic Action

Tumor cells have specific features, including angiogenesis induction, cell cycle dysregulation, and immune destruction evasion. By inducing a T helper type 2 (Th2) immune response, tumor cells may favor immune tolerance within the tumor, which allows progression of cancer growth. Drugs with potentia...

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Detalles Bibliográficos
Autores principales: Silva, Daiana K. Frade, Duarte, Sâmia S., Lisboa, Thaís M. H., Ferreira, Rafael C., Lopes, Ana Luíza de O., Carvalho, Deyse C. M., Rodrigues-Mascarenhas, Sandra, da Silva, Patricia Mirella, Segundo, Miguel A. S. Pinheiro, de Moura, Ricardo O., Medeiros, Karina C. P., Sobral, Marianna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982894/
https://www.ncbi.nlm.nih.gov/pubmed/31861795
http://dx.doi.org/10.3390/molecules25010029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982894/
https://www.ncbi.nlm.nih.gov/pubmed/31861795
http://dx.doi.org/10.3390/molecules25010029

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