Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study
BACKGROUND: To evaluate the presence of oral lesions in a group of patients with primary Sjögren’s syndrome (pSS) and compare these results with a matched control group (CG). MATERIAL AND METHODS: An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medicina Oral S.L.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982992/ https://www.ncbi.nlm.nih.gov/pubmed/31880282 http://dx.doi.org/10.4317/medoral.23254 |
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author | Serrano, Julia López-Pintor, Rosa María Fernández-Castro, Mónica Ramírez, Lucía Sanz, Mariano Casañas, Elisabeth García, Jesús Alberto Recuero, Sheila Bohorquez, Cristina Hernández, Gonzalo |
author_facet | Serrano, Julia López-Pintor, Rosa María Fernández-Castro, Mónica Ramírez, Lucía Sanz, Mariano Casañas, Elisabeth García, Jesús Alberto Recuero, Sheila Bohorquez, Cristina Hernández, Gonzalo |
author_sort | Serrano, Julia |
collection | PubMed |
description | BACKGROUND: To evaluate the presence of oral lesions in a group of patients with primary Sjögren’s syndrome (pSS) and compare these results with a matched control group (CG). MATERIAL AND METHODS: An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) diagnosed according to the American European Criteria (2002), and 122 matched control patients (120 women, 2 men, mean age 60.02±13.13) were included. Demographic and medical data, oral lesions and salivary flow rate were collected. RESULTS: Compared with the controls, pSS patients were 3.95 more likely to have oral lesions (OR 3.95; 95% CI 2.06-7.58; p=0.0001). 57.4% pSS patients presented oral lesions compared to 25.4% in CG. The most common were candidiasis (13.1% vs 2.5%), traumatic lesions (13.1% vs 4.1%), apthae (8.2% vs 0), and fissuration of the tongue (8.2% vs 0.8%). pSS patients with oral lesions had lower salivary flow levels (stimulated and unstimulated), although these differences were not significant. Significant associations were found between the presence of oral lesions and systemic manifestations and history of parotid gland enlargement in pSS patients. CONCLUSIONS: pSS patients suffer more oral lesions than general population and these lesions may aggravate the pSS disease. Key words:Sjögren’s syndrome, oral lesions, oral diseases, oral manifestations, oral disorders. |
format | Online Article Text |
id | pubmed-6982992 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-69829922020-01-29 Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study Serrano, Julia López-Pintor, Rosa María Fernández-Castro, Mónica Ramírez, Lucía Sanz, Mariano Casañas, Elisabeth García, Jesús Alberto Recuero, Sheila Bohorquez, Cristina Hernández, Gonzalo Med Oral Patol Oral Cir Bucal Research BACKGROUND: To evaluate the presence of oral lesions in a group of patients with primary Sjögren’s syndrome (pSS) and compare these results with a matched control group (CG). MATERIAL AND METHODS: An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) diagnosed according to the American European Criteria (2002), and 122 matched control patients (120 women, 2 men, mean age 60.02±13.13) were included. Demographic and medical data, oral lesions and salivary flow rate were collected. RESULTS: Compared with the controls, pSS patients were 3.95 more likely to have oral lesions (OR 3.95; 95% CI 2.06-7.58; p=0.0001). 57.4% pSS patients presented oral lesions compared to 25.4% in CG. The most common were candidiasis (13.1% vs 2.5%), traumatic lesions (13.1% vs 4.1%), apthae (8.2% vs 0), and fissuration of the tongue (8.2% vs 0.8%). pSS patients with oral lesions had lower salivary flow levels (stimulated and unstimulated), although these differences were not significant. Significant associations were found between the presence of oral lesions and systemic manifestations and history of parotid gland enlargement in pSS patients. CONCLUSIONS: pSS patients suffer more oral lesions than general population and these lesions may aggravate the pSS disease. Key words:Sjögren’s syndrome, oral lesions, oral diseases, oral manifestations, oral disorders. Medicina Oral S.L. 2020-01 2019-12-24 /pmc/articles/PMC6982992/ /pubmed/31880282 http://dx.doi.org/10.4317/medoral.23254 Text en Copyright: © 2020 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Serrano, Julia López-Pintor, Rosa María Fernández-Castro, Mónica Ramírez, Lucía Sanz, Mariano Casañas, Elisabeth García, Jesús Alberto Recuero, Sheila Bohorquez, Cristina Hernández, Gonzalo Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title | Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title_full | Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title_fullStr | Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title_full_unstemmed | Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title_short | Oral lesions in patients with primary Sjögren’s syndrome. A case-control cross-sectional study |
title_sort | oral lesions in patients with primary sjögren’s syndrome. a case-control cross-sectional study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982992/ https://www.ncbi.nlm.nih.gov/pubmed/31880282 http://dx.doi.org/10.4317/medoral.23254 |
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