Discovery of [1,2,4]Triazole Derivatives as New Metallo-β-Lactamase Inhibitors

The emergence and spread of metallo-β-lactamase (MBL)-mediated resistance to β-lactam antibacterials has already threatened the global public health. A clinically useful MBL inhibitor that can reverse β-lactam resistance has not been established yet. We here report a series of [1,2,4]triazole deriva...

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Detalles Bibliográficos
Autores principales: Yuan, Chen, Yan, Jie, Song, Chen, Yang, Fan, Li, Chao, Wang, Cheng, Su, Huiling, Chen, Wei, Wang, Lijiao, Wang, Zhouyu, Qian, Shan, Yang, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982996/
https://www.ncbi.nlm.nih.gov/pubmed/31877988
http://dx.doi.org/10.3390/molecules25010056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982996/
https://www.ncbi.nlm.nih.gov/pubmed/31877988
http://dx.doi.org/10.3390/molecules25010056

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